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Novel NNA-DNA Adducts as Biomarkers for Detecting Exposure to Thirdhand Smoke

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
NNA-derived specific adducts represent an integrated biomarker of exposure to thirdhand smoke (THS) as NNA is unique to THS. The NNA-dG covalent binding adduct could serve as such a biomarker, and play a role in identifying individuals exposed to THS, thus providing critical information for early detection and prevention.
Hang, Bo (Lafayette, CA)
The Regents of the University of California (Oakland CA)
14/ 659,588
March 16, 2015
STATEMENT OF GOVERNMENTAL SUPPORT [0002] This invention was made during work supported by U.S. Department of Energy under Contract No. DE-AC02-05CH11231 and by Grant Nos. 19XT-0070 and 19ST-0185 awarded by the Tobacco-Related Disease Research Program (TRDRP) of the State of California. The government has certain rights in this invention.