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RECOMBINANT BACILLUS SUBTILIS THAT CAN GROW ON PLANT BIOMASS

United States Patent Application

20160002645
A1
View the Complete Application at the US Patent & Trademark Office
In certain embodiments recombinant modified microorganisms (e.g., Gram-positive bacteria, yeasts, etc.) are provided that display on their surface a minicellulosome comprising two or more cellulolytic enzymes where the minicellulosome is self-assembled by the microorganism and resulting microorganism is capable of growing on untreated plant biomass (e.g. biomass that is not acid treated and/or enzymatically pre-digested). In certain embodiments the microorganism grows on lignocellulose as the sole carbon source.
Clubb, Robert T. (Culver City, CA), Anderson, Timothy (St. Louis, MO)
14/ 443,031
November 15, 2013
STATEMENT OF GOVERNMENTAL SUPPORT [0002] This invention was made with Government support of Grant No: DE-FC02-02ER63421, awarded by the U.S. Department of Energy. The Government has certain rights in this invention.