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Advanced Drug Development and Manufacturing

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical. For estimating the binding selectivities of a chemical versus chemical analogs, for measuring post translational modification of proteins, and for drug manufacturing.
Birnbaum, Eva R. (Los Alamos, NM), Koppisch, Andrew T. (Flagstaff, AZ), Baldwin, Sharon M. (Santa Fe, NM), Warner, Benjamin P. (Los Alamos, NM), McCleskey, T. Mark (Los Alamos, NM), Berger, Jennifer A. (Los Alamos, NM), Stewart, Jeffrey J. (Cary, NC), Harris, Michael N. (Los Alamos, NM), Burrell, Anthony K. (Naperville, IL)
14/ 693,094
April 22, 2015
STATEMENT REGARDING FEDERAL RIGHTS [0002] This invention was made with government support under Contract No. DE-AC52-06NA25396 awarded by the U.S. Department of Energy. The government has certain rights in the invention.