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GENETICALLY ENGINEERED MICROBES AND METHODS FOR CONVERTING ORGANIC ACIDS TO ALCOHOLS

United States Patent Application

20150275238
A1
View the Complete Application at the US Patent & Trademark Office
Disclosed herein are genetically engineered microbes. In one embodiment, a genetically engineered microbe includes a metabolic pathway for the production of an alcohol from an organic acid. For instance, a genetically engineered microbe converts acetate, butyrate, propionate, isobutyrate, valerate, isovalerate, caproate, or phenylacetate, to Ethanol, Butanol, Propanol, Isobutanol, 1-Pentanol, Isoamylalcohol, 1-Hexanol, Phenylethanol, respectively. Also provided herein are methods of using the microbes.
Kelly, Robert M. (Raleigh, NC), Adams, Michael W.W. (Athens, GA), Schut, Gerrit J. (Athens, GA), Basen, Mirko (Frankfurt, DE)
14/ 670,601
March 27, 2015
GOVERNMENT FUNDING [0002] The present invention was made with government support under DE-AR0000081 and DE-13502-06ER64304, awarded by the Department of Energy, and CBET-1264052/CBET-1264053, awarded by the National Science Foundation. The government has certain rights in the invention.