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IN VIVO AND IN VITRO CARBENE INSERTION AND NITRENE TRANSFER REACTIONS CATALYZED BY HEME ENZYMES

United States Patent Application

20150267232
A1
View the Complete Application at the US Patent & Trademark Office
This invention relates to the use of heme-containing enzymes to catalyze carbene and nitrene insertion and transfer reactions with greater selectivity, mild reaction conditions, and convenient production.
COELHO, PEDRO (Los Angeles, CA), Arnold, Frances H. (La Canada, CA), Lewis, Jared C. (Chicago, IL), Wang, Zhan (San Jose, CA)
California Institute of Technology (Pasadena CA)
14/ 676,744
April 1, 2015
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT [0002] This invention was made with government support under DE-FG02-06ER15762/T-105789 awarded by the Department of Energy and under 1F32EB015846-01. The government has certain rights in the invention.