Skip to Content
Return to Search

Variants of Glycoside Hydrolases

United States Patent Application

*** PATENT GRANTED ***
20150056664
9,701,951
A1
View the Complete Application at the US Patent & Trademark Office
National Renewable Energy Laboratory - Visit the NREL Technology Transfer Website
The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, and optionally further comprising a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2 a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2, wherein the variants have glycoside hydrolase activity. The present invention also relates to nucleotide sequences encoding the variant glycoside hydrolases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.
Teter, Sarah (Mountainview, CA), Ward, Connie (Hamilton, MT), Cherry, Joel (Winters, CA), Jones, Aubrey (Davis, CA), Harris, Paul (Carnation, WA), Yi, Jung (Sacramento, CA)
14/ 475,639
September 3, 2014
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT [0002] This invention was made with Government support under NREL Subcontract No. ZCO-30017-02, Prime Contract DE-AC36-98G010337 awarded by the Department of Energy. The government has certain rights in this invention.