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CELLULASE VARIANTS WITH IMPROVED EXPRESSION, ACTIVITY AND STABILITY, AND USE THEREOF

United States Patent Application

*** PATENT GRANTED ***
20140302585
9,523,087
A1
View the Complete Application at the US Patent & Trademark Office
The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
AEHLE, Wolfgang (Zwingenberg, DE), BOTT, Richard R. (Burlingame, CA), BOWER, Benjamin S. (Newark, CA), CASPI, Jonathan (Sunnyvale, CA), ESTELL, David A. (San Francisco, CA), GOEDEGEBUUR, Frits (Vlaardingen, NL), HOMMES, Ronaldus Wilhelmus (Haarlem, NL), KAPER, Thijs (Half Moon Bay, CA), KELEMEN, Bradley R. (Menlo Park, CA), KRALJ, Slavko (Oegstgeest, NL), VAN LIESHOUT, Johannes Franciscus Thomas (Utrecht, NL), NIKOLAEV, Igor (Noordwijk, NL), VAN STIGT THANS, Sander (Zevenbergen, NL), WALLACE, Louise (Redwood City, CA), VOGTENTANZ, Gudrun (Sunnyvale, CA), SANDGREN, Mats (Uppsala, SE)
DANISCO US INC. (Palo Alto CA)
14/ 189,943
February 25, 2014
[0002] This invention was made with Government support under conditional award no: DE-FC36-08GO18078 awarded by the Department of Energy. The Government has certain rights in this invention.