Skip to Content
Find More Like This
Return to Search

BIOSENSOR BASED ON THE INNATE IMMUNE SYSTEM

United States Patent Application

20140295407
A1
View the Complete Application at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
Described herein are biosensors for early, pre-symptomatic detection of infectious agents and methods for their use. In particular, this disclosure describes biosensors that utilize toll-like receptor (TLR) binding domains to detect pathogen-associated molecular patterns (PAMPs). Also provided herein are methods of detecting and/or capturing a PAMP from a biological sample using the disclosed biosensors.
Swanson, Basil I. (Los Alamos, NM), Mukundan, Harshini (Los Alamos, NM), Chaudhary, Anu (Seattle, WA)
Los Alamos National Security, LLC
14/ 228,170
March 27, 2014
ACKNOWLEDGMENT OF GOVERNMENT SUPPORT [0002] This invention was made with government support under Contract No. DE-AC52-06NA25396 awarded by the U.S. Department of Energy. The government has certain rights in the invention.