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In Vivo Unnatural Amino Acid Expression in the Methylotrophic Yeast Pichia Pastoris

United States Patent Application

*** PATENT GRANTED ***
20140287464
9,732,349
A1
View the Complete Application at the US Patent & Trademark Office
The invention provides orthogonal translation systems for the production of polypeptides comprising unnatural amino acids in methylotrophic yeast such as Pichia pastoris. Methods for producing polypeptides comprising unnatural amino acids in methylotrophic yeast such as Pichia pastoris are also provided.
Young, Travis (San Diego, CA), Schultz, Peter G. (La Jolla, CA)
14/ 165,199
January 27, 2014
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT [0002] The invention was made with government support under Contract No. GM062159 awarded by the National Institutes of Health and under DE-FG03-00ER46051 awarded by the Department of Energy. The government has certain rights in this invention.