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TANNIN-CONTAINING GASTROINTESTINAL FORMULATIONS AND METHODS OF USE

United States Patent Application

20140200266
A1
View the Complete Application at the US Patent & Trademark Office
Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
Reed, Jess Dreher (Madison, WI), Shanmuganayagam, Dhanansayan (Madison, WI), Krueger, Christian Gerald (Cambridge, WI), Kudsk, Kenneth Allan (Madison, WI), Pierre, Joseph Francis (Chicago, IL), Heneghan, Aaron F. (Middleton, WI), Feliciano, Rodrigo P. (Madison, WI)
WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison WI)
14/ 152,267
January 10, 2014
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH [0002] This invention was made with government support under DE-FC02-07ER64494 awarded by the US Department of Energy. The government has certain rights in the invention.