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RAPID AND HIGHLY FIELDABLE VIRAL DIAGNOSTIC

United States Patent Application

*** PATENT GRANTED ***
20140272943
9,523,132
A1
View the Complete Application at the US Patent & Trademark Office
Oak Ridge National Laboratory - Visit the Partnerships Directorate Website
The present invention relates to a rapid, highly fieldable, nearly reagentless diagnostic to identify active RNA viral replication in a live, infected cells, and more particularly in leukocytes and tissue samples (including biopsies and nasal swabs) using an array of a plurality of vertically-aligned nanostructures that impale the cells and introduce a DNA reporter construct that is expressed and amplified in the presence of active viral replication.
McKnight, Timothy E. (Greenback, TN)
UT-Battelle, LLC (Oak Ridge TN)
14/ 212,718
March 14, 2014
[0002] This invention was made with government support under Prime Contract No. DE-AC05-00OR22725 awarded by the U.S. Department of Energy. The government has certain rights in the invention.