The present invention provides for the manipulation of carbon flux in a recombinant host cell to increase the formation of desirable products. The invention relates to cellulose-digesting organisms that have been genetically modified to allow the production of ethanol at a high yield by redirecting carbon flux at key steps of central metabolism.
STATEMENT REGARDING FEDERALLY-SPONSORED RESEARCH AND DEVELOPMENT
 This invention was funded, in part, by the United States government under a Department of Energy Biomass Program award # DE-FC36-07G017057. This invention was also funded, in part, by the BioEnergy Science Center (BESC) under the DOE Office of Science through award number DE-POS2-06ER64304. The U.S. Government has certain rights in this invention.