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PLATFORM FOR IMMOBILIZATION AND OBSERVATION OF SUBCELLULAR PROCESSES

United States Patent Application

20140329308
A1
View the Complete Application at the US Patent & Trademark Office
Oak Ridge National Laboratory - Visit the Partnerships Directorate Website
A method of immobilizing matter for imaging that includes providing an array of nanofibers and directing matter to the array of the nanofibers. The matter is immobilized when contacting at least three nanofibers of the array of nanofibers simultaneously. Adjacent nanofibers in the array of nanofibers may be separated by a pitch as great as 100 microns. The immobilized matter on the array of nanofibers may then be imaged. In some examples, the matter may be cell matter, such as protoplasts.
McKnight, Timothy E. (Greenback, TN), Kalluri, Udaya C. (Knoxville, TN), Melechko, Anatoli V. (Raleigh, NC)
UT-BATTELLE, LLC (Oak Ridge TN)
14/ 338,699
July 23, 2014
[0002] This invention was made with Government support under Contract No. DE-AC05-000R22725 awarded by the United States Department of Energy. The Government has certain rights in this invention.