Herein are described a set of novel specific human enhancers for specific forebrain cell types used to study and select for human neural progenitor cells. This approach enables the ability to generate interneurons from human ES, iPS and iN cells, making them available for human transplantation and for molecular/cellular analyses. These approaches are also directly applicable to generating other neuronal cell types, such as cortical and striatal projection neurons, which have implications for many human diseases.
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 This work was supported Grant Nos. HG003988 awarded by the National Human Genome Research Institute, Grant Nos. MH081880 and MH049428 awarded by the NIH-NIMH, Grant Nos. NS062859A and NS071785 awarded by the NIH-NINDS, by Grant Nos. RB2-01602 and RC1-00346-1 awarded by the California Institute for Regenerative Medicine, and by Contract DE-AC02-05CH11231 awarded by the Department of Energy. The government has certain rights in the invention.