In one embodiment, a system includes a plurality of metal nanoparticles functionalized with a plurality of organic molecules tethered thereto, each organic molecule having a primary face and a secondary face. The plurality of organic molecules preferentially interact with the one or more analytes when placed in proximity therewith. The plurality of organic molecules comprise one or more of: one or more modifying groups on the primary face in place of one or more primary hydroxyl groups; and one or more modifying groups on the secondary face in place of one or more secondary hydroxyl groups. At least one of the one or more analytes is an energetic compound. In another embodiment, a method includes chemically modifying a plurality of cyclodextrin molecules at a primary hydroxyl moiety to create a chemical handle; and tethering the plurality of cyclodextrin molecules to a metal nanoparticle using the chemical handle.
 The United States Government has rights in this invention pursuant to Contract No. DE-AC52-07NA27344 between the United States Department of Energy and Lawrence Livermore National Security, LLC for the operation of Lawrence Livermore National Laboratory.