Disclosed are catalysts, especially catalytic anodes, useful for catalyzing reactions in fuel cells and in other environments. The catalysts have a substrate base made of iridium and/or ruthenium. There is a very thin coating on the substrate which is a mix of platinum and at least one metal selected from gold, palladium, iridium, rhodium, ruthenium, rhenium, and osmium. The anodes are resistant to carbon monoxide adulteration in fuel cells.
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH/DEVELOPMENT
 This invention was made with government support under DE-FG-02-05ER 15731 and DE-AC02-98CH10886 awarded by the Department of Energy. The government has certain rights in the invention.