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Cholesterol Ester Transfer Protein (CETP) Inhibitor Polypeptide Antibodies for Prophylactic and Therapeutic Anti-Atherosclerosis Treatments

United States Patent Application

20140328851
A1
View the Complete Application at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
Herein are described two antibodies that can inhibit CETP-lipoproteins interaction and CETP activity. Presently described are an antibody or fragment thereof capable of specifically binding to an epitope of the N-terminal or C-terminal domains of CETP and methods of using these antibodies for separation, identification, diagnosis and therapy.
Ren, Gang (El Cerrito, CA), Zhang, Lei (Albany, CA)
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland CA)
14/ 279,182
May 15, 2014
STATEMENT OF GOVERNMENTAL SUPPORT [0002] The invention was made with government support under Contract No. DE-AC02-05CH11231 awarded by the U.S. Department of Energy under. The government has certain rights in the invention.