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INFLUENZA SENSOR

United States Patent Application

20060003318
A1
View the Complete Application at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
A sensor for the detection of tetrameric multivalent neuraminidase within a sample is disclosed, where a positive detection indicates the presence of a target virus within the sample. Also disclosed is a trifunctional composition of matter including a trifunctional linker moiety with groups bonded thereto including (a) an alkyl chain adapted for attachment to a substrate, (b) a fluorescent moiety capable of generating a fluorescent signal, and (c) a recognition moiety having a spacer group of a defined length thereon, the recognition moiety capable of binding with tetrameric multivalent neuraminidase.
Swanson, Basil I. (Los Alamos, NM), Song, Xuedong (Los Alamos, NM), Unkefer, Clifford (Los Alamos, NM), Silks, Louis A. III (Los Alamos, NM), Schmidt, Jurgen G. (Los Alamos, NM)
11/ 132,130
May 17, 2005
FIELD OF THE INVENTION [0002] The present invention relates to a diagnostic sensor for the detection of influenza virus and to a method of detecting influenza virus with such a diagnostic sensor. This invention was made with government support under Contract No. W-7405-ENG-36 awarded by the U.S. Department of Energy. The government has certain rights in the invention.