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CURRENT-CARRYING NANOWIRE HAVING A NANOPORE FOR HIGH-SENSITIVITY DETECTION AND ANALYSIS OF BIOMOLECULES

United States Patent Application

20130186758
A1
View the Complete Application at the US Patent & Trademark Office
Disclosed are devices that feature nanopores formed in graphene sheets, such as graphene ribbons. The graphene sheets include an edge irregularity, such as a zig-zag configuration, a chiral edge, or an armchair-configuration edge, which edges confer on the devices the ability to discriminate between different subunits of a macromolecule translocated through the nanpore. The disclosed devices and methods have application to DNA sequencing and analysis, among other applications.
SAHA, Kamal K. (Newark, DE), NIKOLIC, Branislav K. (North East, MD), DRNDIC, Marija (Philadelphia, PA)
University Of Delaware (Newark DE), The Trustees Of The University Of Pennsylvania (Philadelphia PA)
13/ 706,060
December 5, 2012
STATEMENT OF GOVERNMENT RIGHTS [0002] This work was supported by Department of Energy Grant DE-FG02-07ER46374, by National Institutes of Health Grants R21HG004767 and R21HG006313, and by National Science Foundation grant TG-DMR100002.