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Methods and compositions related to a matrix chip

United States Patent Application

20050142534
A1
View the Complete Application at the US Patent & Trademark Office
Lawrence Livermore National Laboratory - Visit the Industrial Partnerships Office Website
Embodiments of the invention relate to devices and methods for evaluating the interactions between cells and between cells and matrix materials wherein the cellular distribution patterns formed as a result of such interactions are indicators of the invasive potential(s) of the cells. Furthermore, such devices and methods can provide indications of the preferred sites of metastasis of invasive cells; the efficacy of an anti-cancer drug applied to such cells; and the potential for agents to promote or enhance tumor growth or metastasis.
Maniotis, Andrew J. (Berwyn, IL), Folberg, Robert (Northbrook, IL)
The Board of Trustees of the University of Illinois
10/ 963,921
October 13, 2004
[0002] The government may own rights in the present invention pursuant to grant number ROI EY 10457 from the National Institutes of Health and grant number W-7405-ENG-48 from the Department of Energy.