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Photoswitchable method for the ordered attachment of proteins to surfaces

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Lawrence Livermore National Laboratory - Visit the Industrial Partnerships Office Website
Disclosed herein is an improved method for the attachment of proteins to any solid support with control over the orientation of the attachment. The method is extremely efficient, not requiring the previous purification of the protein to be attached, and can be activated by UV-light. Spatially addressable arrays of multiple protein components can be generated by using standard photolithographic techniques.
Camarero, Julio A. (Livermore, CA), De Yoreo, James J. (Clayton, CA), Kwon, Youngeun (Livermore, CA)
The Regents of the University of California
10/ 918,759
August 12, 2004
[0002] The United States Government has rights in this invention pursuant to Contract No. W-7405-ENG-48 between the United States Department of Energy and the University of California for the operation of Lawrence Livermore National Laboratory.