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SORTING PROCESS OF NANOPARTICLES AND APPLICATIONS OF SAME

United States Patent Application

20120281213
A1
View the Complete Application at the US Patent & Trademark Office
In one aspect of the present invention, a method for sorting nanoparticles includes preparing a high-viscosity density gradient medium filled in a container, dispersing nanoparticles into an aqueous solution to form a suspension of the nanoparticles, each nanoparticle having one or more cores and a shell encapsulating the one or more cores, layering the suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container, and centrifugating the layered suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container at a predetermined speed for a predetermined period of time to form a gradient of fractions of the nanoparticles along the container, where each fraction comprises nanoparticles in a respective one of aggregation states of the nanoparticles.
TYLER, TIMOTHY P. (CHICAGO, IL), HENRY, ANNE-ISABELLE (CHICAGO, IL), VAN DUYNE, RICHARD P. (WILMETTE, IL), HERSAM, MARK C. (WILMETTE, IL)
NORTHWESTERN UNIVERSITY (EVANSTON IL)
13/ 461,521
May 1, 2012
STATEMENT AS TO RIGHTS UNDER FEDERALLY-SPONSORED RESEARCH [0003] This invention was made with government support under FA9550-08-1-0221 awarded by Air Force Office of Scientific Research, under DE-SC0001059 awarded by Department of Energy, and under DMR0520513 and DMR1006391 awarded by National Science Foundation. The government has certain rights in the invention.