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VOLUME-LABELED NANOPARTICLES AND METHODS OF PREPARATION

United States Patent Application

20120267585
A1
View the Complete Application at the US Patent & Trademark Office
Oak Ridge National Laboratory - Visit the Partnerships Directorate Website
Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.
Wang, Wei (Oak Ridge, TN), Gu, Baohua (Oak Ridge, TN), Retterer, Scott T. (Knoxville, TN), Doktycz, Mitchel J. (Knoxville, TN)
UT-BATTELLE, LLC (Oak Ridge TN)
13/ 489,618
June 6, 2012
GOVERNMENT SUPPORT [0002] This invention was made with government support under Prime Contract No. DE-ACO5-00OR22725 awarded by the U.S. Department of Energy. The U.S. government has certain rights in this invention.