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Design and Implementation of Novel and/or Enhanced Bacterial Microcompartments for Customizing Metabolism

United States Patent Application

20120210459
A1
View the Complete Application at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
Herein is described a bacterial microcompartment catalog comprising a total of 634 gene sequences encoding bacterial microcompartments, the proteins of each can be inserted into a host organism and if needed, expressed using an inducible expression system. Disclosed are at least 32 types of gene clusters which provide microcompartments having metabolizing or other enzyme activity. The expression of these microcompartments can be used to provide or enhance an organism's carbon fixation and/or sequestration activity or biomass production or, generally speaking additional or enhanced metabolic activities to an organism.
Kerfeld, Cheryl A. (Walnut Creek, CA), Loque, Dominique (Albany, CA)
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland CA)
13/ 367,260
February 6, 2012
STATEMENT OF GOVERNMENTAL SUPPORT [0002] This invention was made with government support under Contract No. DE-AC02-05CH11231 awarded by U.S. Department of Energy. The government has certain rights in this invention.