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Method to Predict Responsiveness of Breast Cancer to Polyamine-Type Chemotherapy

United States Patent Application

20110183336
A1
View the Complete Application at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
Methods of-identifying a basal or luminal phenotype of a cell, comprising detecting expression of one or more of a set of predictive biomarker genes or proteins that identify the cell as having a basal or luminal cancer subtype and compositions for treating identified basal or luminal cancers.
GRAY, JOE W. (SAN FRANCISCO, CA), DAS, DEBOPRIYA (ALBANY, CA), KUO, WEN-LIN (SAN RAMON, CA), WANG, NICHOLAS J. (BURLINGAME, CA), NEVE, RICHARD M. (SAN MATEO, CA), SPELLMAN, PAUL T. (BENICIA, CA), FRIDLYAND, JANE (BERKELEY, CA), CHIN, KOEI (FOSTER CITY, CA), HU, ZHI (EL CERRITO, CA)
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (OAKLAND CA)
12/ 767,725
April 26, 2010
STATEMENT OF GOVERNMENTAL SUPPORT [0002] The invention described and claimed herein was made in part under Work for Others Agreement LB7003395 with Progen Pharma, under Grant No. U54 CA112970 awarded by the National Institutes of Health/National Cancer Institute and under Contract No. DE-AC02-05CH11231 awarded by the U.S. Department of Energy. The United States Government has certain rights in this invention.