A calorimeter for use in measuring a sample is provided. The calorimeter may include a sample chamber for housing the sample therein. A separate reference chamber may not be present in the calorimeter. The calorimeter may also have a sample thermoelectric cooler in which heat from the sample chamber is transferred to the sample thermoelectric cooler. A reference thermoelectric cooler for use in detecting thermal noise may also be present, and outputs from the sample thermoelectric cooler and the reference thermoelectric cooler may be used in a control equation to determine the heat output of the sample.
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT
 This invention was made with Government support under Contract No. DE-AC09-96SR18500 awarded by the United States Department of Energy. The Government has certain rights in the invention.