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United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
The present invention relates, in general, to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same. The invention further relates to methods that use a genetic algorithm to create sets of polyvalent antigens suitable for use, for example, in vaccination strategies.
Korber, Bette T. (Los Alamos, NM), Perkins, Simon (Los Alamos, NM), Bhattacharya, Tanmoy (Los Alamos, NM), Fischer, William M. (Los Alamos, NM), Theiler, James (Los Alamos, NM), Letvin, Norman (Boston, MA), Haynes, Barton F. (Durham, NC), Hahn, Beatrice H. (Birmingham, AL), Yusim, Karina (Los Alamos, NM), Kuiken, Carla (Los Alamos, NM)
Los Alamos National Security, LLC (Los Alamos NM), Beth Israel Deaconess Medical Center (Boston MA), Duke University (Durham NC), The University of Alabama at Birmingham Research Foundation (Birmingham AL)
12/ 960,287
December 3, 2010
[0002] This invention was made with Government support under Contract No. DE-AC52-06NA25396 awarded by the U.S. Department of Energy. The Government has certain rights in the invention.