Skip to Content
Find More Like This
Return to Search

HIGH THROUGHPUT FIBER OPTICAL ASSEMBLY FOR FLUORESCENCE SPECTROMETRY

United States Patent Application

20110140001
A1
View the Complete Application at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
System for high-throughput detection of the presence of an analyte of interest in a sample, said system comprising a multi-well plate sample container; an automated means for successively transporting samples from the multi-well plate sample container to a transparent capillary contained within a sample holder; an excitation source in optical communication with the sample, wherein radiation from the excitation source is directed along the length of the capillary, and wherein the radiation induces a signal which is emitted from the sample; and, at least one linear array comprising: a proximal end disposed in proximity to the sample holder and a single end port distal from the proximal end; a plurality of optical fibers extending from the proximal end to the end port and having a first end and a second end, wherein the first ends of the individual optical fibers are arranged substantially parallel and adjacent to one another, and wherein the second ends of the optical fibers form a non-linearly arranged bundle, and wherein the plurality of optical fibers transmits the fluorescent signal from the proximal end to the end port; and an end port assembly optically coupled to the end port, the end port assembly comprising a single photo-detector, wherein the photo-detector detects the fluorescent signal and converts the fluorescent signal into an electrical signal.
Piltch, Martin S. (Los Alamos, NM), Gray, Perry Clayton (Fairfax, VA)
LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos NM)
12/ 966,665
December 13, 2010
STATEMENT REGARDING FEDERAL RIGHTS [0002] This invention was made with government support under Contract No. DE-AC52-06 NA 25396, awarded by the U.S. Department of Energy. The government has certain rights in the invention.