A thermalcycler for processing a sample holder includes a first thermalcycler body with a first face and a second thermalcycler body with a second face. A cavity for receiving the sample holder is formed in at least one of the first face or the second face. A thermalcycling unit is operatively connected to the cavity.
 The United States Government has rights in this invention pursuant to Contract No. W-7405-ENG-48 between the United States Department of Energy and the University of California for the operation of Lawrence Livermore National Laboratory.