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Methods and materials for the production of D-lactic acid in yeast

United States Patent Application

20040029256
A1
View the Complete Application at the US Patent & Trademark Office
The present invention relates to biocatalysts that are cells, optimally of the Crabtree-negative phenotype, comprising expression vectors encoding genes heterologous to the cell that enable increased production of organic products. More specifically, the invention relates to genetically modified Kluyveromyces cells, methods for making the Kluyveromyces cells, and their use in production of organic products, particularly D-lactic acid.
Rajgarhia, Vineet (Minnetonka, MN), Dundon, Catherine Asleson (Minneapolis, MN), Olson, Stacey (St. Bonifacius, MN), Suominen, Pirkko (Maple Grove, MN), Hause, Ben (Jordan, MN)
10/ 449,978
May 30, 2003
[0002] This invention was made with Government support under Contract No. DE-FC36-00GO10598 awarded by the Department of Energy. The government has certain rights in this invention